Bioinformatics

SGS genome assembly Platform

2010 Sequencing technologies — the next generation Human Genome Sequencing Center and Department of Molecular & Human Genetics, Baylor College of Medicine Nature reviews Demand has never been greater for revolutionary technologies that deliver fast, inexpensive and accurate genome information. This challenge has catalysed the development of next-generation sequencing (NGS) technologies. The inexpensive production Read more…

By zywang, ago
Bioinformatics

Long reads genome assembly

https://github.com/isovic/racon https://github.com/PacificBiosciences/FALCON https://github.com/marbl/canu 2015 Assembling large genomes with single-molecule sequencing and locality-sensitive hashing Department of Chemistry and Biochemistry, University of Maryland Nature Biotechnology  

By zywang, ago
Bioinformatics

BAUM – Improving Genome Assembly by Adaptive Unique Mapping and Local Overlap-Layout-Consensus

Download our soft from  http://www.zhanyuwang.xin/BAUM/BAUMsoft.tar.gz (alternative download url: https://www.dropbox.com/s/7qzgb4035lln608/BAUMsoft.tar.gz) Abstract Motivation: It is highly desirable to assemble genomes of high continuity and consistency at low cost. The current bottleneck of draft genome continuity using the Second Generation Sequencing (SGS) reads is primarily caused by uncertainty among repetitive sequences. Even though the Read more…

By zywang, ago